Nitro/Nitrosyl-Ruthenium Complexes Are Potent and Selective Anti-Trypanosoma cruzi Agents Causing Autophagy and Necrotic Parasite Death

cis-[RuCl(NO(2))(dppb)(5,5′-mebipy)] (complex 1), cis-[Ru(NO(2))(2)(dppb)(5,5′-mebipy)] (complex 2), ct-[RuCl(NO)(dppb)(5,5′-mebipy)](PF(6))(2) (complex 3), and cc-[RuCl(NO)(dppb)(5,5′-mebipy)](PF(6))(2) (complex 4), where 5,5′-mebipy is 5,5′-dimethyl-2,2′-bipyridine and dppb is 1,4-bis(diphenylphos...

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Bibliographische Detailangaben
Hauptverfasser: Bastos, Tanira M., Barbosa, Marília I. F., da Silva, Monize M., da C. Júnior, José W., Meira, Cássio S., Guimaraes, Elisalva T., Ellena, Javier, Moreira, Diogo R. M., Batista, Alzir A., Soares, Milena B. P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187982/
https://ncbi.nlm.nih.gov/pubmed/25092707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02765-14
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