Nitro/Nitrosyl-Ruthenium Complexes Are Potent and Selective Anti-Trypanosoma cruzi Agents Causing Autophagy and Necrotic Parasite Death

cis-[RuCl(NO(2))(dppb)(5,5′-mebipy)] (complex 1), cis-[Ru(NO(2))(2)(dppb)(5,5′-mebipy)] (complex 2), ct-[RuCl(NO)(dppb)(5,5′-mebipy)](PF(6))(2) (complex 3), and cc-[RuCl(NO)(dppb)(5,5′-mebipy)](PF(6))(2) (complex 4), where 5,5′-mebipy is 5,5′-dimethyl-2,2′-bipyridine and dppb is 1,4-bis(diphenylphos...

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Bibliografiske detaljer
Main Authors: Bastos, Tanira M., Barbosa, Marília I. F., da Silva, Monize M., da C. Júnior, José W., Meira, Cássio S., Guimaraes, Elisalva T., Ellena, Javier, Moreira, Diogo R. M., Batista, Alzir A., Soares, Milena B. P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Experimental Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187982/
https://ncbi.nlm.nih.gov/pubmed/25092707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02765-14
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