Agmatine-Containing Poly(amidoamine)s as a Novel Class of Antiviral Macromolecules: Structural Properties and In Vitro Evaluation of Infectivity Inhibition

Poly(amidoamine)s (PAAs) are multifunctional tert-amine polymers endowed with high structural versatility. Here we report on the screening of a minilibrary of PAAs against a panel of viruses. The PAA AGMA1 showed antiviral activity against herpes simplex virus, human cytomegalovirus, human papilloma...

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Autores principales: Donalisio, Manuela, Ranucci, Elisabetta, Cagno, Valeria, Civra, Andrea, Manfredi, Amedea, Cavalli, Roberta, Ferruti, Paolo, Lembo, David
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187951/
https://ncbi.nlm.nih.gov/pubmed/25092704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03420-14
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