The Agmatine-Containing Poly(Amidoamine) Polymer AGMA1 Binds Cell Surface Heparan Sulfates and Prevents Attachment of Mucosal Human Papillomaviruses

The agmatine-containing poly(amidoamine) polymer AGMA1 was recently shown to inhibit the infectivity of several viruses, including human papillomavirus 16 (HPV-16), that exploit cell surface heparan sulfate proteoglycans (HSPGs) as attachment receptors. The aim of this work was to assess the antivir...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Cagno, Valeria, Donalisio, Manuela, Bugatti, Antonella, Civra, Andrea, Cavalli, Roberta, Ranucci, Elisabetta, Ferruti, Paolo, Rusnati, Marco, Lembo, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538463/
https://ncbi.nlm.nih.gov/pubmed/26077258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00443-15
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