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Drug Target Identification Using a Trypanosome Overexpression Library
Elucidation of molecular targets is very important for lead optimization during the drug development process. We describe a direct method to find targets of antitrypanosomal compounds against Trypanosoma brucei using a trypanosome overexpression library. As proof of concept, we treated the library w...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4187942/ https://ncbi.nlm.nih.gov/pubmed/25049244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03338-14 |
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