Identification of FDA-Approved Drugs as Antivirulence Agents Targeting the pqs Quorum-Sensing System of Pseudomonas aeruginosa

The long-term use of antibiotics has led to the emergence of multidrug-resistant bacteria. A promising strategy to combat bacterial infections aims at hampering their adaptability to the host environment without affecting growth. In this context, the intercellular communication system quorum sensing...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: D'Angelo, Francesca, Baldelli, Valerio, Halliday, Nigel, Pantalone, Paolo, Polticelli, Fabio, Fiscarelli, Ersilia, Williams, Paul, Visca, Paolo, Leoni, Livia, Rampioni, Giordano
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2018
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Mechanisms of Action: Physiological Effects
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201120/
https://ncbi.nlm.nih.gov/pubmed/30201815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01296-18
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