Identification of Mechanisms for Attenuation of the FSC043 Mutant of Francisella tularensis SCHU S4

Previously, we identified a spontaneous, essentially avirulent mutant, FSC043, of the highly virulent strain SCHU S4 of Francisella tularensis subsp. tularensis. We have now characterized the phenotype of the mutant and the mechanisms of its attenuation in more detail. Genetic and proteomic analyses...

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Detalhes bibliográficos
Main Authors: Lindgren, Marie, Tancred, Linda, Golovliov, Igor, Conlan, Wayne, Twine, Susan M., Sjöstedt, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187832/
https://ncbi.nlm.nih.gov/pubmed/24935978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01406-13
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