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Distinct Regions of NLRP1B Are Required To Respond to Anthrax Lethal Toxin and Metabolic Inhibition

Pattern recognition receptors monitor for signs of infection or cellular dysfunction and respond to these events by initiating an immune response. NLRP1B is a receptor that upon activation recruits multiple copies of procaspase-1, which promotes cytokine processing and a proinflammatory form of cell...

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Detalles Bibliográficos
Main Authors: Neiman-Zenevich, Jana, Liao, Kuo-Chieh, Mogridge, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187829/
https://ncbi.nlm.nih.gov/pubmed/24935976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02167-14
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