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Identification of receptor-binding domains on human interleukin 5 and design of an interleukin 5-derived receptor antagonist.

A detailed structure-function analysis of human interleukin 5 (hIL5) has been performed. The hIL5 receptor is composed of two different polypeptide chains, the alpha and beta subunits. The alpha subunit alone is sufficient for ligand binding, but association with the beta subunit leads to a 2- to 3-...

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Main Authors: Tavernier, J, Tuypens, T, Verhee, A, Plaetinck, G, Devos, R, Van der Heyden, J, Guisez, Y, Oefner, C
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC41875/
https://ncbi.nlm.nih.gov/pubmed/7761472
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