Detailed analysis of the IL-5-IL-5R alpha interaction: characterization of crucial residues on the ligand and the receptor.

The receptor for interleukin-5 (IL-5) is composed of two different subunits. The IL-5 receptor alpha (IL-5R alpha) is required for ligand-specific binding while association with the beta-chain results in increased binding affinity. Murine IL-5 (mIL-5) has similar activity on human and murine cells,...

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Detalhes bibliográficos
Main Authors: Cornelis, S, Plaetinck, G, Devos, R, Van der Heyden, J, Tavernier, J, Sanderson, C J, Guisez, Y, Fiers, W
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC394406/
https://ncbi.nlm.nih.gov/pubmed/7628440
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