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Histone deacetylase 1 reduces NO production in endothelial cells via lysine deacetylation of NO synthase 3
The lysine acetylation state of nonhistone proteins may be regulated through histone deacetylases (HDACs). Evidence suggests that nitric oxide (NO) synthase 3 (NOS3; endothelial NOS) is posttranslationally lysine acetylated, leading to increased NO production in the endothelium. We tested the hypoth...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Physiological Society
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4187392/ https://ncbi.nlm.nih.gov/pubmed/25015965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00243.2014 |
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