Mitochondrial uncoupling does not decrease reactive oxygen species production after ischemia-reperfusion

Cardiac ischemia-reperfusion (IR) leads to myocardial dysfunction by increasing production of reactive oxygen species (ROS). Mitochondrial H(+) leak decreases ROS formation; it has been postulated that increasing H(+) leak may be a mechanism of decreasing ROS production after IR. Ischemic preconditi...

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Bibliographic Details
Main Authors: Quarrie, Ricardo, Lee, Daniel S., Reyes, Levy, Erdahl, Warren, Pfeiffer, Douglas R., Zweier, Jay L., Crestanello, Juan A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2014
Subjects:
Energetics and Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187075/
https://ncbi.nlm.nih.gov/pubmed/25085966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00189.2014
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