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Mitochondrial fission in endothelial cells following simulated ischemia/reperfusion: Role of nitric oxide and reactive oxygen species

Ischemia (I)/reperfusion (RP)-induced endothelial cell (EC) injury is thought to occur due to mitochondrial reactive oxygen species (mtROS) production. MtROS have been implicated in mitochondrial fission. We determined whether cultured EC exposure to simulated I/RP causes morphological changes in th...

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Bibliographische Detailangaben
Hauptverfasser: Giedt, Randy J., Yang, Changjun, Zweier, Jay L., Matzavinos, Anastasios, Alevriadou, B. Rita
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253175/
https://ncbi.nlm.nih.gov/pubmed/22100972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.10.491
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