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Mitochondrial fission in endothelial cells following simulated ischemia/reperfusion: Role of nitric oxide and reactive oxygen species

Ischemia (I)/reperfusion (RP)-induced endothelial cell (EC) injury is thought to occur due to mitochondrial reactive oxygen species (mtROS) production. MtROS have been implicated in mitochondrial fission. We determined whether cultured EC exposure to simulated I/RP causes morphological changes in th...

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Detalhes bibliográficos
Main Authors: Giedt, Randy J., Yang, Changjun, Zweier, Jay L., Matzavinos, Anastasios, Alevriadou, B. Rita
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253175/
https://ncbi.nlm.nih.gov/pubmed/22100972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.10.491
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