Selective ligands of estrogen receptor β discovered using pharmacophore mapping and structure-based virtual screening

AIM: To discover novel ligands of estrogen receptor (ER) β using pharmacophore mapping and structure-based screening. METHODS: A computer-aided strategy combining pharmacophore mapping and structure-based screening was used to screen the Maybridge and Enamine databases. Yeast two-hybrid (Y2H) assay...

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Main Authors: Chen, Lei, Wu, Dang, Bian, Han-ping, Kuang, Guang-lin, Jiang, Jing, Li, Wei-hua, Liu, Gui-xia, Zou, Shi-en, Huang, Jin, Tang, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186986/
https://ncbi.nlm.nih.gov/pubmed/25176400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.69
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