Thyroid Hormone Inactivation in Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) are resistant to traditional chemotherapy but are responsive to the tyrosine kinase inhibitors imatinib and sunitinib.(1) The use of these agents has improved the outcome for patients but is associated with adverse effects, including hypothyroidism.(2) Multipl...

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Autori principali: Maynard, Michelle A., Marino-Enriquez, Adrian, Fletcher, Jonathan A., Dorfman, David M., Raut, Chandrajit P., Yassa, Leila, Guo, Cuicui, Wang, Yuexiang, Dorfman, Clara, Feldman, Henry A., Frates, Mary C., Song, Huaidong, Jugo, Rebecca H., Taguchi, Takahiro, Hershman, Jerome M., Larsen, P. Reed, Huang, Stephen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186889/
https://ncbi.nlm.nih.gov/pubmed/24693892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1308893
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