Thyroid Hormone Inactivation in Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) are resistant to traditional chemotherapy but are responsive to the tyrosine kinase inhibitors imatinib and sunitinib.(1) The use of these agents has improved the outcome for patients but is associated with adverse effects, including hypothyroidism.(2) Multipl...

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Main Authors: Maynard, Michelle A., Marino-Enriquez, Adrian, Fletcher, Jonathan A., Dorfman, David M., Raut, Chandrajit P., Yassa, Leila, Guo, Cuicui, Wang, Yuexiang, Dorfman, Clara, Feldman, Henry A., Frates, Mary C., Song, Huaidong, Jugo, Rebecca H., Taguchi, Takahiro, Hershman, Jerome M., Larsen, P. Reed, Huang, Stephen A.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186889/
https://ncbi.nlm.nih.gov/pubmed/24693892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1308893
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