Thyroid Hormone Inactivation in Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) are resistant to traditional chemotherapy but are responsive to the tyrosine kinase inhibitors imatinib and sunitinib.(1) The use of these agents has improved the outcome for patients but is associated with adverse effects, including hypothyroidism.(2) Multipl...

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Bibliografiske detaljer
Main Authors: Maynard, Michelle A., Marino-Enriquez, Adrian, Fletcher, Jonathan A., Dorfman, David M., Raut, Chandrajit P., Yassa, Leila, Guo, Cuicui, Wang, Yuexiang, Dorfman, Clara, Feldman, Henry A., Frates, Mary C., Song, Huaidong, Jugo, Rebecca H., Taguchi, Takahiro, Hershman, Jerome M., Larsen, P. Reed, Huang, Stephen A.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186889/
https://ncbi.nlm.nih.gov/pubmed/24693892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1308893
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