Thyroid Hormone Inactivation in Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) are resistant to traditional chemotherapy but are responsive to the tyrosine kinase inhibitors imatinib and sunitinib.(1) The use of these agents has improved the outcome for patients but is associated with adverse effects, including hypothyroidism.(2) Multipl...

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Detalhes bibliográficos
Main Authors: Maynard, Michelle A., Marino-Enriquez, Adrian, Fletcher, Jonathan A., Dorfman, David M., Raut, Chandrajit P., Yassa, Leila, Guo, Cuicui, Wang, Yuexiang, Dorfman, Clara, Feldman, Henry A., Frates, Mary C., Song, Huaidong, Jugo, Rebecca H., Taguchi, Takahiro, Hershman, Jerome M., Larsen, P. Reed, Huang, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186889/
https://ncbi.nlm.nih.gov/pubmed/24693892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1308893
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