Thyroid Hormone Inactivation in Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) are resistant to traditional chemotherapy but are responsive to the tyrosine kinase inhibitors imatinib and sunitinib.(1) The use of these agents has improved the outcome for patients but is associated with adverse effects, including hypothyroidism.(2) Multipl...

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Détails bibliographiques
Auteurs principaux: Maynard, Michelle A., Marino-Enriquez, Adrian, Fletcher, Jonathan A., Dorfman, David M., Raut, Chandrajit P., Yassa, Leila, Guo, Cuicui, Wang, Yuexiang, Dorfman, Clara, Feldman, Henry A., Frates, Mary C., Song, Huaidong, Jugo, Rebecca H., Taguchi, Takahiro, Hershman, Jerome M., Larsen, P. Reed, Huang, Stephen A.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186889/
https://ncbi.nlm.nih.gov/pubmed/24693892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1308893
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