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Concomitant Inactivation of Foxo3a and Fancc or Fancd2 Reveals a Two-Tier Protection from Oxidative Stress-Induced Hydrocephalus
Aims: This study seeks at investigating the cause of hydrocephalus, and at identifying therapeutic targets for the prevention of hydrocephalus. Results: In this study, we show that inactivation of the Foxo3a gene in two mouse models of Fanconi anemia (FA) leads to the development of hydrocephalus in...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Mary Ann Liebert, Inc.
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186827/ https://ncbi.nlm.nih.gov/pubmed/24483844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5597 |
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