Concomitant Inactivation of Foxo3a and Fancc or Fancd2 Reveals a Two-Tier Protection from Oxidative Stress-Induced Hydrocephalus

Aims: This study seeks at investigating the cause of hydrocephalus, and at identifying therapeutic targets for the prevention of hydrocephalus. Results: In this study, we show that inactivation of the Foxo3a gene in two mouse models of Fanconi anemia (FA) leads to the development of hydrocephalus in...

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Main Authors: Li, Xiaoli, Li, Liang, Li, Jie, Sipple, Jared, Schick, Jonathan, Mehta, Parinda A., Davies, Stella M., Dasgupta, Biplab, Waclaw, Ronald R., Pang, Qishen
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2014
Fag:
Original Research Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186827/
https://ncbi.nlm.nih.gov/pubmed/24483844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5597
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