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Hemorrhagic Shock Shifts the Serum Cytokine Profile from Pro- to Anti-Inflammatory after Experimental Traumatic Brain Injury in Mice

Secondary insults, such as hemorrhagic shock (HS), worsen outcome from traumatic brain injury (TBI). Both TBI and HS modulate levels of inflammatory mediators. We evaluated the addition of HS on the inflammatory response to TBI. Adult male C57BL6J mice were randomized into five groups (n=4 [naïve] o...

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Bibliographic Details
Main Authors: Shein, Steven L., Shellington, David K., Exo, Jennifer L., Jackson, Travis C., Wisniewski, Stephen R., Jackson, Edwin K., Vagni, Vincent A., Bayır, Hülya, Clark, Robert S.B., Dixon, C. Edward, Janesko-Feldman, Keri L., Kochanek, Patrick M.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186809/
https://ncbi.nlm.nih.gov/pubmed/24773520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2013.2985
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