Severe Brief Pressure-Controlled Hemorrhagic Shock after Traumatic Brain Injury Exacerbates Functional Deficits and Long-Term Neuropathological Damage in Mice

Hypotension after traumatic brain injury (TBI) worsens outcome. We published the first report of TBI plus hemorrhagic shock (HS) in mice using a volume-controlled approach and noted increased neuronal death. To rigorously control blood pressure during HS, a pressure-controlled HS model is required....

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Detalhes bibliográficos
Main Authors: Hemerka, Joseph N., Wu, Xianren, Dixon, C. Edward, Garman, Robert H., Exo, Jennifer L., Shellington, David K., Blasiole, Brian, Vagni, Vincent A., Janesko-Feldman, Keri, Xu, Mu, Wisniewski, Stephen R., Bayır, Hülya, Jenkins, Larry W., Clark, Robert S.B., Tisherman, Samuel A., Kochanek, Patrick M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472682/
https://ncbi.nlm.nih.gov/pubmed/22738159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2011.2303
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