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O4.10 CNS STEM CELL SPECIFIC TUMOURIGENESIS REVEALS LINEAGE RELATIONSHIP BETWEEN EXPERIMENTAL AND HUMAN GLIOMAS AND A DOMINANCE OF GLIAL SIGNATURES DURING TUMOUR PROPAGATION IN VITRO
BACKGROUND: Brain tumors are thought to originate from stem/progenitor cell populations that acquire specific genetic mutations. Although current preclinical models have relevance to human pathogenesis, many do not recapitulate the histogenesis of the human disease. METHODS: and AIMS: We analysed th...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4185672/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.31 |
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