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Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation
The gene responsible for neurofibromatosis type 1 (NF1) encodes a tumor suppressor that functions as a negative regulator of the Ras proto-oncogene. Individuals with germline mutations in NF1 are predisposed to the development of benign and malignant tumors of the peripheral and central nervous syst...
Gorde:
| Egile Nagusiak: | , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2005
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760350/ https://ncbi.nlm.nih.gov/pubmed/16314489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.02162 |
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