O4.10 CNS STEM CELL SPECIFIC TUMOURIGENESIS REVEALS LINEAGE RELATIONSHIP BETWEEN EXPERIMENTAL AND HUMAN GLIOMAS AND A DOMINANCE OF GLIAL SIGNATURES DURING TUMOUR PROPAGATION IN VITRO

BACKGROUND: Brain tumors are thought to originate from stem/progenitor cell populations that acquire specific genetic mutations. Although current preclinical models have relevance to human pathogenesis, many do not recapitulate the histogenesis of the human disease. METHODS: and AIMS: We analysed th...

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Autori principali: Brandner, S., Henriquez, N., Benedykcinska, A., Li, N., Lau, J., Sidlauskas, K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Oral Presentations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185672/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.31
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