P04.17 DIAGNOSTIC VALUE OF PLASMA AND URINARY 2-HYDROXYGLUTARATE TO IDENTIFY PATIENTS WITH IDH-MUTATED GLIOMA

BACKGROUND: Mutation of IDH1 gene is a prognostic factor and a diagnostic hallmark of gliomas. Mutant IDH1 enzyme can convert α-KG into 2-Hydroxyglutarate(2HG); mutated gliomas have elevated amounts of intracellular 2HG. We analyzed 2HG concentration in plasma and urine in glioma patients(PTS) to id...

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Hauptverfasser: Lombardi, G., Corona, G., Farina, P., Puppa, A. Della, Bertorelle, R., Gardiman, M., Toffoli, G., Denaro, L., D'Avella, D., Zagonel, V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
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Poster Presentations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185493/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.149
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