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P04.16 THE BIOMARKER POTENTIAL OF MGMT PROTEIN EXPRESSION IN GLIOBLASTOMA IS IMPROVED BY EXCLUSION OF NON-TUMOR CELLS
INTRODUCTION: Methylation of the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) gene promoter is predictive of benefit from temozolomide (TMZ) in glioblastoma (GBM). Non-tumor cells are numerous in GBMs and a potential source of bias in attempts to determine MGMT status by immunohi...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4185492/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.148 |
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