P04.16 THE BIOMARKER POTENTIAL OF MGMT PROTEIN EXPRESSION IN GLIOBLASTOMA IS IMPROVED BY EXCLUSION OF NON-TUMOR CELLS

INTRODUCTION: Methylation of the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) gene promoter is predictive of benefit from temozolomide (TMZ) in glioblastoma (GBM). Non-tumor cells are numerous in GBMs and a potential source of bias in attempts to determine MGMT status by immunohi...

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Bibliografiske detaljer
Main Authors: Klitkou, J., Dahlrot, R.H., Hansen, S., Kristensen, B.W.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
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Poster Presentations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185492/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.148
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