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P04.16 TP53 mutations in codon 273 is predictive of overall survival in astrocytoma patients

BACKGROUND: Tumour Protein 53 (TP53) is a tumour suppressor gene that is mutated in at least 50% of human malignancies. The prevalence of TP53 mutation is much higher in astrocytomas with reports of up to 75% TP53 mutant cases. Rare cases of TP53 mutation also exist in oligodendroglial tumours (10–1...

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Publicado en:Neuro Oncol
Main Authors: Noor, H, Rapkins, R, McDonald, K
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795968/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.111
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