P04.06 TERT PROMOTER MUTATIONS CONTRIBUTE TO SUBSET PROGNOSTICATION OF LOWER GRADE GLIOMAS

Recurrent mutations in the promoter region of TERT (telomerase reverse transcriptase) have been found in various cancers including diffuse gliomas. Mutations lead to TERT upregulation and are associated with aggressive clinical behaviour in glioblastomas. However, the clinical significance of TERT p...

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Autors principals: Chan, A.K., Yao, Y., Zhang, Z., Chung, N.Y., Li, K.K., Chan, D.T., Poon, W.S., Zhou, L., Ng, H.K.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185481/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.138
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