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P04.06 Temozolomide influence on global DNA methylation in glioblastoma cell lines
BACKGROUND: The gold standard treatment of glioblastoma, the most lethal glioma subtype, includes surgery followed by the combination of radiotherapy and chemotherapy with temozolomide (TMZ). The active metabolite of TMZ methylates DNA bases in several positions, from which methylation of the O6 pos...
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| Опубликовано в: : | Neuro Oncol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6144674/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.240 |
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