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P04.06 PD-L1 Expression is Associated with Wild Type IDH, Immune Response and DNA Damage in Malignant Gliomas

BACKGROUND: Immune-checkpoint inhibition is a promising new approach in glioma therapy. Currently, this therapy is being evaluated for glioblastoma in different clinical trials. Since the molecular mechanism of PD-L1 regulation in gliomas is largely unknown, the present study was initiated.. METHODS...

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Publicat a:Neuro Oncol
Autors principals: Heiland, D. H., Haaker, J. G.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5782582/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now188.084
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