Persistence of hepatitis B virus covalently closed circular DNA in hepatocytes: molecular mechanisms and clinical significance

Covalently closed circular DNA (cccDNA) is the transcriptional template of hepatitis B virus (HBV). Extensive research over the past decades has unveiled the important role of cccDNA in the natural history and antiviral treatment of chronic HBV infection. cccDNA can persist in patients recovering fr...

Full description

Saved in:
Bibliographic Details
Main Authors: Yang, Hung-Chih, Kao, Jia-Horng
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185362/
https://ncbi.nlm.nih.gov/pubmed/26038757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emi.2014.64
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items