Ligation of TLR5 promotes myeloid cell infiltration and differentiation into mature osteoclasts in RA and experimental arthritis

The aim was to examine the impact of TLR5 ligation in rheumatoid arthritis (RA) and experimental arthritis pathology. Studies were conducted to investigate the role of TLR5 ligation on RA and mouse myeloid cell chemotaxis or osteoclast formation; in addition, to uncover the significance of TNF-α fun...

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Autores principales: Kim, Seung-jae, Chen, Zhenlong, Chamberlain, Nathan D., Essani, Abdul B., Volin, Michael V., Amin, M. Asif, Volkov, Suncica, Gravallese, Ellen M., Arami, Shiva, Swedler, William, Lane, Nancy E., Mehta, Anjali, Sweiss, Nadera, Shahrara, Shiva
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185216/
https://ncbi.nlm.nih.gov/pubmed/25200955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302998
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