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Effective Genetic-Risk Prediction Using Mixed Models
For predicting genetic risk, we propose a statistical approach that is specifically adapted to dealing with the challenges imposed by disease phenotypes and case-control sampling. Our approach (termed Genetic Risk Scores Inference [GeRSI]), combines the power of fixed-effects models (which estimate...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4185122/ https://ncbi.nlm.nih.gov/pubmed/25279982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2014.09.007 |
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