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Genetic Variants in CYP2R1, CYP24A1, and VDR Modify the Efficacy of Vitamin D(3) Supplementation for Increasing Serum 25-Hydroxyvitamin D Levels in a Randomized Controlled Trial

CONTEXT: Adequate serum 25-hydroxyvitamin D concentrations, [25(OH)D], are required for optimal bone health, and low levels are associated with chronic diseases. OBJECTIVE: We investigated whether 41 candidate single nucleotide polymorphisms (SNPs) in vitamin D and calcium pathway genes (GC, DHCR7,...

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Bibliografske podrobnosti
Main Authors: Barry, Elizabeth L., Rees, Judy R., Peacock, Janet L., Mott, Leila A., Amos, Christopher I., Bostick, Roberd M., Figueiredo, Jane C., Ahnen, Dennis J., Bresalier, Robert S., Burke, Carol A., Baron, John A.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184076/
https://ncbi.nlm.nih.gov/pubmed/25070320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-1389
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