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Soy phosphatidylinositol containing nanoparticle prolongs hemostatic activity of B-domain deleted Factor VIII in Hemophilia A mice
Factor VIII (FVIII) replacement therapy in Hemophilia A (HA) is complicated by a short half-life and high incidence of inhibitory antibody response against the protein. Phosphatidylinositol (PI) containing lipidic nanoparticles have previously been shown to reduce the immunogenicity and prolong the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183744/ https://ncbi.nlm.nih.gov/pubmed/24700333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23963 |
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