A mechanism for posttranslational modifications of proteins by yeast protein farnesyltransferase.
Protein farnesyltransferase catalyzes the alkylation of cysteine in C-terminal CaaX sequences of a variety of proteins, including Ras, nuclear lamins, large G proteins, and phosphodiesterases, by farnesyl diphosphate (FPP). These modifications enhance the ability of the proteins to associate with me...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1995
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41837/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7761439/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.11.5008 |
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