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A mechanism for posttranslational modifications of proteins by yeast protein farnesyltransferase.

Protein farnesyltransferase catalyzes the alkylation of cysteine in C-terminal CaaX sequences of a variety of proteins, including Ras, nuclear lamins, large G proteins, and phosphodiesterases, by farnesyl diphosphate (FPP). These modifications enhance the ability of the proteins to associate with me...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Dolence, J M, Poulter, C D
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1995
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41837/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7761439/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.11.5008
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