Mycobacterial Antigen Driven Activation of CD14(++)CD16(−) Monocytes Is a Predictor of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome

Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is an aberrant inflammatory response occurring in a subset of TB-HIV co-infected patients initiating anti-retroviral therapy (ART). Here, we examined monocyte activation by prospectively quantitating pro-inflam...

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Autori principali: Andrade, Bruno B., Singh, Amrit, Narendran, Gopalan, Schechter, Melissa E., Nayak, Kaustuv, Subramanian, Sudha, Anbalagan, Selvaraj, Jensen, Stig M. R., Porter, Brian O., Antonelli, Lis R., Wilkinson, Katalin A., Wilkinson, Robert J., Meintjes, Graeme, van der Plas, Helen, Follmann, Dean, Barber, Daniel L., Swaminathan, Soumya, Sher, Alan, Sereti, Irini
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183698/
https://ncbi.nlm.nih.gov/pubmed/25275318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004433
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