Mycobacterial Antigen Driven Activation of CD14(++)CD16(−) Monocytes Is a Predictor of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome

Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is an aberrant inflammatory response occurring in a subset of TB-HIV co-infected patients initiating anti-retroviral therapy (ART). Here, we examined monocyte activation by prospectively quantitating pro-inflam...

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Detalhes bibliográficos
Main Authors: Andrade, Bruno B., Singh, Amrit, Narendran, Gopalan, Schechter, Melissa E., Nayak, Kaustuv, Subramanian, Sudha, Anbalagan, Selvaraj, Jensen, Stig M. R., Porter, Brian O., Antonelli, Lis R., Wilkinson, Katalin A., Wilkinson, Robert J., Meintjes, Graeme, van der Plas, Helen, Follmann, Dean, Barber, Daniel L., Swaminathan, Soumya, Sher, Alan, Sereti, Irini
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183698/
https://ncbi.nlm.nih.gov/pubmed/25275318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004433
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