Differential expression of CXCR3 and CCR6 on CD4(+) T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution inflammatory syndrome

Immune reconstitution inflammatory syndrome (IRIS) occurs in up to 40% of individuals co-infected with pulmonary tuberculosis (PTB) and HIV, primarily upon antiretroviral therapy (ART) initiation. Phenotypic changes in T-cells during TB-IRIS and their relationship with systemic inflammation are not...

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Publicado no:Sci Rep
Main Authors: Silveira-Mattos, Paulo S., Narendran, Gopalan, Akrami, Kevan, Fukutani, Kiyoshi F., Anbalagan, Selvaraj, Nayak, Kaustuv, Subramanyam, Sudha, Subramani, Rajasekaran, Vinhaes, Caian L., Souza, Deivide Oliveira-de, Antonelli, Lis R., Satagopan, Kumar, Porter, Brian O., Sher, Alan, Swaminathan, Soumya, Sereti, Irini, Andrade, Bruno B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365576/
https://ncbi.nlm.nih.gov/pubmed/30728405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37846-3
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