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Both Transmembrane Domains of BK β1 Subunits Are Essential to Confer the Normal Phenotype of β1-Containing BK Channels

Voltage/Ca(2+) (i)-gated, large conductance K(+) (BK) channels result from tetrameric association of α (slo1) subunits. In most tissues, BK protein complexes include regulatory β subunits that contain two transmembrane domains (TM1, TM2), an extracellular loop, and two short intracellular termini. F...

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Autors principals: Kuntamallappanavar, Guruprasad, Toro, Ligia, Dopico, Alex M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183656/
https://ncbi.nlm.nih.gov/pubmed/25275635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109306
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