Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs

[Image: see text] Structural studies of modified nucleobases in RNA duplexes are critical for developing a full understanding of the stability and specificity of RNA base pairing. 2-Thio-uridine (s(2)U) is a modified nucleobase found in certain tRNAs. Thermodynamic studies have evaluated the effects...

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Main Authors: Sheng, Jia, Larsen, Aaron, Heuberger, Benjamin D., Blain, J. Craig, Szostak, Jack W.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183603/
https://ncbi.nlm.nih.gov/pubmed/25188906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja508015a
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