Spred-2 Deficiency Exacerbates Lipopolysaccharide-Induced Acute Lung Inflammation in Mice

BACKGROUND: Acute respiratory distress syndrome (ARDS) is a severe and life-threatening acute lung injury (ALI) that is caused by noxious stimuli and pathogens. ALI is characterized by marked acute inflammation with elevated alveolar cytokine levels. Mitogen-activated protein kinase (MAPK) pathways...

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Main Authors: Xu, Yang, Ito, Toshihiro, Fushimi, Soichiro, Takahashi, Sakuma, Itakura, Junya, Kimura, Ryojiro, Sato, Miwa, Mino, Megumi, Yoshimura, Akihiko, Matsukawa, Akihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183529/
https://ncbi.nlm.nih.gov/pubmed/25275324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108914
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