A Novel Role of Spred2 in the Colonic Epithelial Cell Homeostasis and Inflammation

Rapid and adequate mucosal healing is important for a remission of ulcerative colitis (UC) patients. Here, we examined whether Spred2, a member of the Sprouty-related EVH1-domain-containing proteins that inhibit the Ras/Raf/ERK pathway, plays a role in colonic mucosal homeostasis and inflammation by...

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Publicat a:Sci Rep
Autors principals: Takahashi, Sakuma, Yoshimura, Teizo, Ohkura, Takahiro, Fujisawa, Masayoshi, Fushimi, Soichiro, Ito, Toshihiro, Itakura, Junya, Hiraoka, Sakiko, Okada, Hiroyuki, Yamamoto, Kazuhide, Matsukawa, Akihiro
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116627/
https://ncbi.nlm.nih.gov/pubmed/27869219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37531
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