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Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain

Methylation of the N6 position of selected internal adenines (m(6)A) in mRNAs and noncoding RNAs is widespread in eukaryotes, and the YTH domain in a collection of proteins recognizes this modification. We report the crystal structure of the splicing factor YT521-B homology (YTH) domain of Zygosacch...

詳細記述

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書誌詳細
主要な著者: Luo, Shukun, Tong, Liang
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183320/
https://ncbi.nlm.nih.gov/pubmed/25201973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412742111
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