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Biochemical and structural basis for YTH domain of human YTHDC1 binding to methylated adenine in DNA
The recently characterized mammalian writer (methyltransferase) and eraser (demethylase) of the DNA N6-methyladenine (N6mA) methyl mark act on single-stranded (ss) and transiently-unpaired DNA. As YTH domain-containing proteins bind N6mA-containing RNA in mammalian cells, we investigated whether mam...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7544203/ https://ncbi.nlm.nih.gov/pubmed/32663306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa604 |
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