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Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain
Methylation of the N6 position of selected internal adenines (m(6)A) in mRNAs and noncoding RNAs is widespread in eukaryotes, and the YTH domain in a collection of proteins recognizes this modification. We report the crystal structure of the splicing factor YT521-B homology (YTH) domain of Zygosacch...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183320/ https://ncbi.nlm.nih.gov/pubmed/25201973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412742111 |
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