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Quantification of dexamethasone and corticosterone in rat biofluids and fetal tissue using highly sensitive analytical methods: assay validation and application to a pharmacokinetic study

A sensitive, specific, accurate and precise LC/MS/MS method was developed for the simultaneous measurement of dexamethasone and corticosterone in rat plasma. The method was extended to dexamethasone analysis in rat plasma ultrafiltrate and fetal tissues. Samples were processed using SPE involving Oa...

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Detalhes bibliográficos
Main Authors: Samtani, Mahesh N., Jusko, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183228/
https://ncbi.nlm.nih.gov/pubmed/17385808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bmc.788
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